Holiday Inn Express & Suites Buffalo Downtown - Medical Ctr

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Holiday Inn Express & Suites Buffalo Downtown - Medical Ctr All Suite 100% Non Smoking Hotel walking distance to Shea's, Buffalo Bison's and First Niagara Center Explore & More - Ralph C. Wilson Jr.
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We welcome you to stay at our Holiday Inn Express & Suites Buffalo, located in the heart of downtown near Roswell Park, John R. Oishei Children's Hospital, Buffalo General Hospital, Convention Center and Canalside. Hotel parking is offsite and available nearby at additional charge in parking garage. Enjoy being nestled in the heart of the Theatre District, where you can experience a grand performance at Shea's Performing Arts Center or the Irish Classical Theatre. Take in a concert at the Town Ballroom or TRALF located within the same block or hop on the above ground trolley train to the Key Bank Center. Children's Museum and the Naval Park are also just a few blocks away. The city is also packed with events and festivals at Canalside and Sahlen's Field. Admire contemporary art at the Albright-Knox Art Gallery or discover Frank Lloyd Wright's stunning residencies nearby and marvel at the Darwin Martin House. Don't forget to make the 20 mile trip to one of the Nation's North American Wonders of the World - Niagara Falls! For those traveling on business we are in close proximity to M&T Bank, Buffalo Niagara Medical Campus, and New Era Cap. You will appreciate our 24-hour Business Center and Fitness Center.

Where good food and good company come together. Settle in, savor the moment, and enjoy dining done right.
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Where good food and good company come together. Settle in, savor the moment, and enjoy dining done right.

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Checking in to make some memories?
Sky’s the limit.

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Touchdown-worthy bites await. 🏈🍔 Make Holiday Inn by IHG your game day headquarters with great food, refreshing drinks, ...
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Touchdown-worthy bites await. 🏈🍔 Make Holiday Inn by IHG your game day headquarters with great food, refreshing drinks, and all the comforts you need for a winning weekend.

Step into a stay full of character. At every Holiday Inn – the niu, vibrant interiors, unique local influences, and thou...
10/15/2026

Step into a stay full of character. At every Holiday Inn – the niu, vibrant interiors, unique local influences, and thoughtfully designed guest rooms come together to create a memorable experience from check-in to checkout.

A good meeting starts with great ideas. A great meeting starts with the right space. 💡 Discover flexible gathering space...
10/13/2026

A good meeting starts with great ideas. A great meeting starts with the right space. 💡 Discover flexible gathering spaces designed to inspire collaboration at Holiday Inn .

More shared meals. More laughter around the table. More moments like this. 💚 Make memories together at Holiday Inn by IH...
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More shared meals. More laughter around the table. More moments like this. 💚 Make memories together at Holiday Inn by IHG.

Whatever brings you together, it all feels easier here. From big meetings to small moments, you’ll find the space and su...
09/29/2026

Whatever brings you together, it all feels easier here. From big meetings to small moments, you’ll find the space and support to gather well at Holiday Inn.

Stepping into vacation, one easy moment at a time 🌴✨At Holiday Inn Resort by IHG, the only plan is to take it slow and e...
09/24/2026

Stepping into vacation, one easy moment at a time 🌴✨

At Holiday Inn Resort by IHG, the only plan is to take it slow and enjoy the stay.

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Game on. 🎮 Our new gaming pods have arrived at participating Holiday Inn hotels across Saudi Arabia, offering a fun new ...
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Game on. 🎮 Our new gaming pods have arrived at participating Holiday Inn hotels across Saudi Arabia, offering a fun new way to play, connect, and make memories together.

Available at:
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Your welcome comes with a twist. Our full-service bar is pouring the perfect way to toast your day. *Offerings vary by l...
09/15/2026

Your welcome comes with a twist. Our full-service bar is pouring the perfect way to toast your day.

*Offerings vary by location.

Stay bold, stay local ✨ Holiday Inn – the niu brings modern design and neighborhood stories to life so you can experienc...
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Stay bold, stay local ✨

Holiday Inn – the niu brings modern design and neighborhood stories to life so you can experience Germany like you’ve been here all along.

Start your day the delicious way 🍳✨ Everything you need, all in one breakfast buffet at Holiday Inn by IHG.
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Start your day the delicious way 🍳✨

Everything you need, all in one breakfast buffet at Holiday Inn by IHG.

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The backdrop for your next big idea? A space with a story to tell. Find your focus at Holiday Inn - the niu, where bold design takes its cue from the character and creativity of the neighborhood.

Before the backpacks, bus stops, and busy mornings... there's still time for one more getaway. Start the day with breakf...
08/26/2026

Before the backpacks, bus stops, and busy mornings... there's still time for one more getaway. Start the day with breakfast and make every moment count at Holiday Inn by IHG. 🍳☀️

Palm trees, lush lawns, and days that feel this easy at Holiday Inn Resort Baruna Bali by IHG.
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Palm trees, lush lawns, and days that feel this easy at Holiday Inn Resort Baruna Bali by IHG.

Address

601 Main Street
Buffalo, NY
14203

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