Holiday Inn Express & Suites Houston S - Medical Ctr Area

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Holiday Inn Express & Suites Houston S - Medical Ctr Area Stay Steps Away from NRG Stadium at Holiday Inn Express & Suites Houston S – Medical Center Area.

Experience unbeatable convenience at our hotel, located within walking distance of NRG Stadium perfect for catching a Texans NFL game, major concerts, or exciting events

We’re also minutes from leading medical centers, including Texas Medical Center, Texas Children’s Hospital, and MD Anderson Cancer Center. Explore nearby attractions like the Houston Museum District, Houston Zoo, and The Galleria for world-class shopping and dining

Enjoy a comfortable stay with complimentary breakfast, a refreshing outdoor pool, and a 24-hour Fitness Center. Plus, take advantage of our daily shuttle to nearby medical centers. Whether you’re here for the big game, medical appointments, or a Houston getaway, we put you right where you want to be—steps from NRG Stadium.

10/20/2026

Sweet, savory, stackable, spoonable… wherever you wake up, there’s something tasty to get out of bed for.

A stay that loves your to-do AND your do-not-disturb.
10/15/2026

A stay that loves your to-do AND your do-not-disturb.

10/06/2026

A winning blend: Costa Coffee and Holiday Inn Express.

09/29/2026

Morning motivation comes standard: Free hot breakfast and Costa Coffee at Holiday Inn Express.

*Offerings vary by region.

09/25/2026

Keep rolling, we’ve got you covered. Everything you need to rest, recharge, and fuel up is ready at Holiday Inn Express by IHG.

09/23/2026

We saved you a spot. It’s next to the cinnamon rolls.

*Offerings vary by region.

09/21/2026

*Books stay for breakfast*

*Offerings vary by region.

It's love at first sip. *Offerings vary by region.
09/19/2026

It's love at first sip.

*Offerings vary by region.

09/17/2026

Game day’s sweetest start.

*Offerings vary by region.

09/16/2026

Wherever you travel, we're there. Cheering you on.

Sleep like you mean it. Rooms designed for maximum comfort, featuring plush duvets, pillow options, and sparkling-clean ...
08/31/2026

Sleep like you mean it. Rooms designed for maximum comfort, featuring plush duvets, pillow options, and sparkling-clean spaces, so you can snooze with confidence.

08/30/2026

Our REM cycle runs on pancakes. Dreamy breakfast + Costa Coffee, free at Holiday Inn Express.

*Offerings vary by region.

Address

9300 S Main Street
Houston, TX
77025

Telephone

+18323719300

Website

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