Hilton Jacksonville at Mayo Clinic Near Beaches

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Hilton Jacksonville at Mayo Clinic Near Beaches

Where Coastal Cool Meets Southern Charm at Jacksonville’s Iconic Host situated near the Intracoastal Waters and pristine beaches. Home to Coastal Kitchen.

Book now and share your stay at . Hilton Jacksonville at Mayo Clinic brings a new chapter of purpose-driven hospitality to Northeast Florida. Located just one mile from Mayo Clinic’s renowned campus, our full‑service flagship hotel merges wellness, design, and convenience. Perfect for medical travelers, families, business guests, and explorers of Jacksonville. Key features:
Prime location: 4745 Transformation Way, under 1 mile to the Mayo Clinic, 4 miles to UNF, 5 miles to the beaches, and 6 miles to St. Johns Town Center

Seamless arrival:
Onsite self‑parking, on‑site EV charging, free Wi‑Fi throughout public spaces. Warm & restorative amenities:
Outdoor pool, fitness center, in‑room dining, and Coastal Kitchen restaurant, all crafted with guest's well‑being in mind. Flexible spaces:
Over 21,000 sqft of indoor and outdoor venues, ideal for meetings, wellness retreats, or family celebrations

Guest‑centric service:
Concierge, digital check‑in/key, and Hilton CleanStay standards for a safer, seamless stay

Our 8‑story, 252‑room hotel is officially open, reservations at
https://www.hilton.com/en/hotels/jaxmohh-hilton-jacksonville-at-mayo-clinic/

10/06/2026

Breast Cancer Awareness Month holds special meaning for us at , steps from a campus dedicated to advancing care and research.

As Official Host Hotel of the National Marathon to Finish Breast Cancer, a signature event of The DONNA Foundation, we stand behind a mission to provide hope, support, and financial relief to those living with breast cancer.

10/03/2026

A little movement, a little stillness, and a lot of good company at this fall, hosted by Yoga Tour de Jax YTJ

Yoga & Brunch: Sunday, October 4 at 9:00 AM, with brunch available at

Yoga on the Lawn: Saturday, October 17 at 9:00 AM
Yoga & Brunch: Sunday, November 1 at 10:00 AM

Arrive 15 minutes early, as class begins promptly.
Reserve your spot at https://bit.ly/4y5I2PH

10/01/2026

One year ago, the lights came on at 4745 Transformation Way.

Since then: thousands of guests, hundreds of gatherings in the Northstar Ballroom, countless meals and drinks at , and numerous awards. Each one is part of the same promise: wellness, connection, celebration, and the stay.

09/29/2026

Some of the best work happens away from the office.

Fast Wi-Fi, better coffee, and a desk with no one stopping by to chat. Then the laptop closes, and the beaches are only minutes away from .

09/27/2026

A boat named Northstar once carried Dr. William Worrall Mayo across open water.

Today, it lends its name to a ballroom built for milestones of its own.

The Northstar Ballroom at holds weddings, galas, and gatherings worth navigating toward.

Start planning your event at https://ow.ly/cQ2150ZJB9U

09/25/2026

Cabana life starts early at .

Shade, splashes, and the whole afternoon poolside. ResortPass gets you in this weekend, no overnight stay needed.

Reserve yours at resortpass.com/hotels/hilton-jacksonville-at-mayo-clinic

09/24/2026

We’re honored to share that our team at has been nominated for a 2026 ConventionSouth Readers’ Choice Award.

The Readers’ Choice Award highlights destinations and hotels known for providing exceptional professionalism and service. If we’ve helped make your meeting, wedding, or social event a memorable experience, please take a moment to vote for us.

We’re also proud to see Visit Jacksonville recognized with a nomination alongside us.

Winners will be featured in the December issue. Voting is now open through Sunday, October 4, 2026 at 11:59 PM.

Vote through conventionsouth.com/readers-choice-award-voting-florida/

09/22/2026

The day starts softly at .

Sunrise over the pool, coffee within reach, and no reason to rush any of it.

09/21/2026

Tomorrow marks the first day of fall, though Jacksonville barely notices the change. The guest room still invites you to exhale, and the pool deck still calls your name at .

09/20/2026

The vows are yours. The rest is handled.

From the Northstar Ballroom to the morning-after brunch at , every detail is anticipated before you even ask.

Learn more about weddings at through https://ow.ly/WSf350ZJAXx

Address

4745 Transformation Way
Jacksonville, FL
32224

Website

https://www.hilton.com/en/hotels/jaxmohh-hilton-jacksonville-at-mayo-clinic

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