Holiday Inn Express & Suites Perryville I-55

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Holiday Inn Express & Suites Perryville I-55 Welcome to our Holiday Inn Express and Suites Perryville, MO. Our hotel is located just off I-55 exit 129. Our hotel offers 75 rooms including 18 suites.

Whether you're traveling for a business or leisure stay, our Perryville, MO hotel provides premium guest amenities and excellent services. Our hotel offers 100% smoke free guest rooms and facilities, heated indoor pool for relaxation, a fitness center, free high speed WI-FI, flat screen LED TV's, microwave and refrigerator. Our hotel is also equipped with a conference room tailored to meet your business needs. Our hotel Holiday Inn Express and Suites is minutes away from Perryville downtown and Perryville Historic Attractions including Association of the Miraculous Medal, Missouri's National Veterans Memorial Wall, Lutheran Heritage Center and Museum, River Heritage Region and Saxon Lutheran Memorial. Business guests appreciate an easy commute to area companies, including TG Missouri, Gilster-Mary Lee, Sabreliner Aviation, PCMH (Perry County Memorial Hospital), CHG Healthcare, Jackson Healthcare, Robinson Construction and Buchheit Inc. Don't forget to stop by for our hot complimentary breakfast bar. We look forward to your next visit.

10/20/2026

Sweet, savory, stackable, spoonable… wherever you wake up, there’s something tasty to get out of bed for.

A stay that loves your to-do AND your do-not-disturb.
10/15/2026

A stay that loves your to-do AND your do-not-disturb.

10/06/2026

A winning blend: Costa Coffee and Holiday Inn Express.

09/29/2026

Morning motivation comes standard: Free hot breakfast and Costa Coffee at Holiday Inn Express.

*Offerings vary by region.

09/25/2026

Keep rolling, we’ve got you covered. Everything you need to rest, recharge, and fuel up is ready at Holiday Inn Express by IHG.

09/23/2026

We saved you a spot. It’s next to the cinnamon rolls.

*Offerings vary by region.

09/21/2026

*Books stay for breakfast*

*Offerings vary by region.

It's love at first sip. *Offerings vary by region.
09/19/2026

It's love at first sip.

*Offerings vary by region.

09/17/2026

Game day’s sweetest start.

*Offerings vary by region.

09/16/2026

Wherever you travel, we're there. Cheering you on.

Sleep like you mean it. Rooms designed for maximum comfort, featuring plush duvets, pillow options, and sparkling-clean ...
08/31/2026

Sleep like you mean it. Rooms designed for maximum comfort, featuring plush duvets, pillow options, and sparkling-clean spaces, so you can snooze with confidence.

08/30/2026

Our REM cycle runs on pancakes. Dreamy breakfast + Costa Coffee, free at Holiday Inn Express.

*Offerings vary by region.

Address

2020 Jefferson Street
Perryville, MO
63775

Telephone

+15736051385

Website

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