Holiday Inn Express & Suites Rochester – Mayo Clinic Area

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Holiday Inn Express & Suites Rochester – Mayo Clinic Area Holiday Inn Express & Suites Rochester is located across from St. Mary’s Hospital & just less than a mile from Mayo Clinic & Rochester Methodist Hospital

Hotel By St Mary's Hospital - Rochester Mayo Clinic
Welcome to the Holiday Inn Express & Suites Rochester - Mayo Clinic Area hotel, located just 2.5 blocks west of St. Mary’s Hospital, and less than a mile from Mayo Clinic, the Gonda building, and the Eisenberg building. You'll find us on the corner of Hwy 52 and 2nd Street SW, making it easy to come and go as you please from our underground heated parking garage. Our hotel offers shuttle service to the hospital and clinic on weekdays for your convenience if you don't want to drive. And the Rochester International Airport is only 9 miles from us. The Rochester Holiday Inn Express is a great hotel for families while visiting the area. We are near some of Rochester's best attractions including the Mayo Civic Center, Silver Lake, Minnesota Children's Museum of Rochester, and the History Center of Olmsted County. After a long day, we hope you take the chance to visit one of the great local restaurants we have near the hotel like Canadian Honker, Cafe Presto, or Tonic that are just steps away from our door. We are even near popular chain restaurants including TGI Fridays, Olive Garden, and Famous Dave's. We hope your stay at the Holiday Inn Express Rochester, MN is a pleasant one.

10/20/2026

Sweet, savory, stackable, spoonable… wherever you wake up, there’s something tasty to get out of bed for.

A stay that loves your to-do AND your do-not-disturb.
10/15/2026

A stay that loves your to-do AND your do-not-disturb.

10/06/2026

A winning blend: Costa Coffee and Holiday Inn Express.

09/29/2026

Morning motivation comes standard: Free hot breakfast and Costa Coffee at Holiday Inn Express.

*Offerings vary by region.

09/25/2026

Keep rolling, we’ve got you covered. Everything you need to rest, recharge, and fuel up is ready at Holiday Inn Express by IHG.

09/23/2026

We saved you a spot. It’s next to the cinnamon rolls.

*Offerings vary by region.

09/21/2026

*Books stay for breakfast*

*Offerings vary by region.

It's love at first sip. *Offerings vary by region.
09/19/2026

It's love at first sip.

*Offerings vary by region.

09/17/2026

Game day’s sweetest start.

*Offerings vary by region.

09/16/2026

Wherever you travel, we're there. Cheering you on.

Sleep like you mean it. Rooms designed for maximum comfort, featuring plush duvets, pillow options, and sparkling-clean ...
08/31/2026

Sleep like you mean it. Rooms designed for maximum comfort, featuring plush duvets, pillow options, and sparkling-clean spaces, so you can snooze with confidence.

08/30/2026

Our REM cycle runs on pancakes. Dreamy breakfast + Costa Coffee, free at Holiday Inn Express.

*Offerings vary by region.

Address

155 16th Avenue SW
Rochester, MN
55902

Telephone

+15072268700

Website

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